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Eye Colour and Heredity: How it Works

Eye colour is a fascinating subject that combines genetics, biology and a hint of mystery. 

The basics of eye colour

Eye colour is determined by the amount and type of pigment in the iris. The two primary pigments are melanin (brown hues) and lipochrome (yellow hues). The combination and distribution of these pigments produce the different eye colours we see, including brown, blue, green, gray and variations in between.

The genes involved

Traditionally, scientists believed that a single gene with dominant and recessive alleles controlled eye colour. The simple model stipulated that brown eyes were dominant over blue eyes. However, modern research has revealed that the reality is far more complex.

The heredity model

Here's a simplified explanation of how these genes can influence eye colour:

  • Brown eyes: Individuals with a high concentration of melanin in the iris will have brown eyes. This is often due to versions of the OCA2 and HERC2 genes that favour high melanin production.
  • Blue eyes: A low concentration of melanin leads to blue eyes. This condition is often the result of genetic variations that decrease the activity of genes responsible for melanin production.
  • Green eyes and other variations: Green eyes result from an intermediate amount of melanin, often influenced by other genes and genetic variations. Grey and hazel eyes also result from different combinations of pigments and their distribution in the iris.

Probabilities and variations

The genetics of eye colour operate on a probabilistic basis. For example, two brown-eyed parents can have a blue-eyed child if each carries recessive alleles for the colour blue. Genetic mutations and recombinations add a further layer of variability.

Practical examples

  • Brown-eyed parents can have children with brown, green or blue eyes, depending on their specific alleles.
  • The children of one brown-eyed parent and one blue-eyed parent are more likely to have brown eyes but may also have blue or green eyes.
  • Two blue-eyed parents will likely have blue-eyed children, but rare mutations or specific genetic combinations could produce green eyes.

Eye colour is a fascinating example of the complexity of human genetics. What we perceive as simple variations in hue result from multiple genetic interactions. Science continues to explore these mechanisms, revealing new layers of complexity and beauty daily in how our traits are inherited and expressed. 

So, the next time you come across someone with sparkling green eyes or deep brown ones, you'll know there's a lot more to them than meets the eye. Genetics, in collaboration with the environment, tell a rich and complex story behind every pair of eyes.

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